{"id":5785,"date":"2021-12-14T15:18:26","date_gmt":"2021-12-14T20:18:26","guid":{"rendered":"https:\/\/ptp.cloud\/?p=5785"},"modified":"2025-06-26T02:50:34","modified_gmt":"2025-06-26T06:50:34","slug":"aws-hpc-genomics-life-sciences","status":"publish","type":"post","link":"https:\/\/ptp.cloud\/aws-hpc-genomics-life-sciences\/","title":{"rendered":"Maximizing AWS High Performance Compute for Genomics Workloads in Life Sciences"},"content":{"rendered":"[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221; custom_padding=&#8221;||0px|||&#8221;]\n<p><a href=\"https:\/\/aws.amazon.com\/marketplace\/pp\/prodview-it7fjq6rqix74?sr=0-13&amp;ref_=beagle&amp;applicationId=AWSMPContessa\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-201  alignright\" src=\"https:\/\/ptp.cloud\/wp-content\/uploads\/2020\/07\/aws-seal-256x300.jpg\" alt=\"\" width=\"128\" height=\"150\" \/><\/a><a href=\"https:\/\/www.linkedin.com\/in\/ajeskey\/\"><em>Aaron Jeskey, Senior Cloud Architect<\/em><\/a><\/p>\n<p data-start=\"829\" data-end=\"1173\">In life sciences and running or considering genomics workloads? Don\u2019t overlook the power of AWS High Performance Compute (HPC). As an AWS Advanced Tier Consulting Partner with the Life Sciences Competency, the team at PTP frequently meets biotech and genomics organizations where the cloud infrastructure was inherited without a clear strategy.<\/p>\n<p data-start=\"1175\" data-end=\"1583\">Because AWS allows anyone to spin up instances in minutes, many cloud environments start without architectural planning or alignment to the AWS Well Architected Framework. Often the initial goal is simple\u2014deploy an app, store data, estimate an EC2 instance\u2014and then never revisit it. But managing biotech IT services requires oversight, governance, and optimization to scale efficiently and remain compliant.<\/p>\n<p data-start=\"1585\" data-end=\"2007\">We\u2019re seeing rapid growth in HPC adoption across our life sciences IT support clients due to its power in generating insights faster. Genomics workloads demand high compute power, high-throughput networking, and performant file systems. Application partners like <a data-start=\"1848\" data-end=\"1878\" rel=\"noopener\" target=\"_new\" class=\"\" href=\"https:\/\/quiltdata.com\">Quilt<\/a> and <a data-start=\"1883\" data-end=\"1921\" rel=\"noopener\" target=\"_new\" class=\"\" href=\"https:\/\/www.dotmatics.com\">Dotmatics<\/a> integrate well with HPC but can accelerate cloud spending if not properly configured.<\/p>\n<p>One client asked our team to evaluate their 18-month-old HPC setup that had spiraling costs. Using our Cloud Management Platform powered by CloudCheckr, we discovered the environment was running 24\/7\u2014despite only needing compute power 30% of the time.<\/p>\n<p>By implementing AWS Auto Scaling, we introduced a \u201cheartbeat\u201d HPC cluster to maintain readiness at minimal cost, enabling rapid scaling when needed. The result: a 70% reduction in operational costs for HPC without any performance degradation.<\/p>\n<p>We followed this by conducting an AWS Well Architected Review using nOps, aligning their infrastructure with AWS\u2019s six pillars: Operational Excellence, Performance Efficiency, Security, Cost Optimization, Reliability, and Sustainability. This holistic review helped the client turn a reactive setup into a cost-efficient, compliant, and scalable solution.<\/p>\n<p>Your team knows the chemistry and biology behind your mission. We bring the cloud engineering, security monitoring, and cloud management expertise needed to help your data science team drive faster outcomes\u2014at significantly lower cost.<\/p>\n<p><iframe loading=\"lazy\" title=\"The Secret Behind PeakPlus for Life Sciences\" width=\"1080\" height=\"608\" src=\"https:\/\/www.youtube.com\/embed\/LNP1qSoaY90?feature=oembed\"  allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p data-start=\"236\" data-end=\"454\"><strong data-start=\"236\" data-end=\"274\">About PTP\u2019s Life Sciences Practice<\/strong><br data-start=\"274\" data-end=\"277\" \/>PTP accelerates data science and genomics research by automating workflows and enabling scalable, secure environments for computational biology, chemistry, and machine learning.<\/p>\n<p data-start=\"456\" data-end=\"798\">We design, implement, and\u00a0optimize AWS technology solutions tailored for life sciences and healthcare organizations. From genomics pipelines to research data analytics, our infrastructure expertise helps teams move faster, lower IT costs, and scale operations without compromising compliance.<\/p>\n<p>Based in Boston, we serve the world\u2019s most innovative biotech, biopharma, and healthcare institutions. Whether you&#8217;re a startup in seed funding or a pre-IPO leader, we support managed IT services for life sciences that meet complex regulatory needs\u2014HIPAA, GxP, and beyond. Our team works closely with IT leaders and scientists to deliver flexible, cloud-first architectures that support secure growth and scientific discovery.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n<span class=\"et_bloom_bottom_trigger\"><\/span>","protected":false},"excerpt":{"rendered":"<p>Aaron Jeskey, Senior Cloud Architect In life sciences and running or considering genomics workloads? Don\u2019t overlook the power of AWS High Performance Compute (HPC). As an AWS Advanced Tier Consulting Partner with the Life Sciences Competency, the team at PTP frequently meets biotech and genomics organizations where the cloud infrastructure was inherited without a clear [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":16844,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"In Life Sciences and running or considering running genomics workloads? \u00a0Do not overlook the power of AWS High Performance Compute (HPC). \u00a0As an AWS Advanced Consulting Partner with the Life Sciences Competency, the team at PTP comes across numerous biotech firms where the IT leader or bioinformatician inherited an existing cloud infrastructure. \u00a0Because AWS can be spun up in minutes with a credit card, most of these environments are not initiated with a plan or an architecture (certainly not with alignment to the AWS Well Architected Framework) in mind. \u00a0For the majority there was simply a need for cloud storage or an application to deploy and they estimated the Elastic Compute Cloud (EC2) instance needed and never looked back. \u00a0You are not alone and the answer is not overly tenuous, it simply requires the right tools to analyze and the skills to put a plan in motion.\r\n\r\nWe are seeing a growth in adoption for the use of <a href=\"https:\/\/aws.amazon.com\/hpc\/\">High Performance Computing (HPC) <\/a>for our Life Sciences customers due to its value in gaining insights and driving results faster. \u00a0Organizations running genomics workloads require more compute, higher performance file systems and high throughput networking. \u00a0Solutions from Life Sciences application partners like <a href=\"https:\/\/quiltdata.com\">Quilt<\/a> and <a href=\"https:\/\/www.dotmatics.com\">Dotmatics<\/a> can be highly leveraged with HPC. \u00a0However, without proper oversight, compute costs can grow rapidly. \u00a0In one particular case, the PTP team was brought in to review an existing 18-month old HPC environment with sharply increasing costs. \u00a0Through analysis with our Cloud Management Platform from <a href=\"https:\/\/cloudcheckr.com\">CloudCheckr<\/a>, the team identified that this environment was built to be continuously running, yet their needs were for only 30% of the month.\r\n\r\nBy leveraging AWS Auto Scaling, the PTP team added configurations that kept a heartbeat HPC cluster, a sliver of the always-on cost, allowing for scaling and expansion when needed. \u00a0This work resulted in a <strong>70% cost reduction<\/strong> for the overall operations of the HPC for the genomics workloads with zero impact to performance. \u00a0The next step in this process was to conduct an <a href=\"https:\/\/ptp.cloud\/aws-well-architected-review\/\">AWS Well Architected Review (WAR)<\/a> with the tools platform from PTP partner <a href=\"https:\/\/www.nops.io\">nOps<\/a>. \u00a0This work analyzes the overall AWS environment against the 6 pillars of the <a href=\"https:\/\/aws.amazon.com\/architecture\/well-architected\/?wa-lens-whitepapers.sort-by=item.additionalFields.sortDate&wa-lens-whitepapers.sort-order=desc\">AWS Well Architected Framework<\/a>: Operational Excellence, Performance Efficiency, Security, Cost-Optimization, Reliability and recently added Sustainability.\r\n\r\nYour teams know the chemistry and the biology and the goals for your research and data analytics. \u00a0PTP knows the AWS cloud, security, cloud networking and cloud management and has the resources to empower your data science team to drive results faster, at a lower cost.\r\n\r\n<a href=\"https:\/\/www.linkedin.com\/in\/ajeskey\/\"><em>Aaron Jeskey, Senior Cloud Architect<\/em><\/a>\r\n<h5>About <a href=\"https:\/\/ptp.cloud\/aws-for-life-sciences-practice\/\">PTP's Life Sciences Practice<\/a><\/h5>\r\n<em>Accelerating the pace of data science through automation, enhanced workflow resulting in trusted computational biology, chemistry, data science and machine learning.<\/em>\r\n\r\nPTP architects, implements and optimizes AWS technology solutions that enable life sciences and healthcare organizations to develop faster, lower IT costs, and scale their operations. The AWS platform is trusted by the largest enterprises and the hottest startups alike to power a wide variety of workloads, including web and mobile applications, application development, data processing, warehousing, storage, archive and much more.\r\nWe are located in the Boston area, the hub of some of the most innovative companies and research institutions in the world in the life sciences, biotech, biopharma and healthcare spaces. We work with companies from start-up to seed funding, from public to pre-IPO, to help them meet security compliance requirements (HIPAA, GxP, etc.), reduce infrastructure costs, improve operational efficiencies, and ultimately innovate faster. Working alongside their IT teams, or directly with their scientists, we design and deploy flexible infrastructure solutions on AWS.\r\n\r\n\u00a0\r\n\r\n[embed]https:\/\/www.youtube.com\/watch?v=LNP1qSoaY90[\/embed]","_et_gb_content_width":"","content-type":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[23,12,34,1],"tags":[],"table_tags":[],"class_list":["post-5785","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aws-archive","category-aws-for-life-sciences-archive","category-finops-archive","category-news-archive"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>AWS HPC for Genomics: Reduce Costs &amp; Boost Performance in Life Sciences<\/title>\n<meta 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